Description: This mouse model harbors a transgene that deletes 2.7kb of intron 23 in the Ift88 gene resulting in a null allele. Heterozygous mice are phenotypically normal. Homozygous mice in the FVB background develop multiple embryonic defects including preaxial polydactyly, hydrocephalus and cystic kidneys and can survive to 7-21 days of age.
Contact: info@pkd-rrc.org

Note: Additional combinations of alleles are available upon request