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Mouse Kidney Cell Lines, Primary Cells, Embryonic Fibroblasts, IMCD Cells

Overview of Cell Models available from the PKD RRC

*NEW* Immortalized mouse Pkd1fl/fl, Pax8rtTA-Cre; mTmG cells (Clone #413– Medulla)

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*NEW* Immortalized mouse Pkd1fl/fl, Pax8rtTA-Cre cells (Clone #313 – Medulla)

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*NEW* Immortalized mouse Pkd1fl/fl, Pax8rtTA-Cre cells (Clone #302 – Cortex)

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Immortalized mouse Pkd2fl/fl, Pax8rtTA-Cre cells (Clone #125)

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Immortalized mouse Pkd1fl/fl, Pax8rtTA-Cre cells (Clone #199)

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mIMCD3 Flp-In T-Rex

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mIMCD3 Flp-In T-Rex PKD1 KO

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PKD1 Null Mouse Embryonic Fibroblasts and control

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PKD2 Null Mouse Embryonic Fibroblasts and control

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Material Transfer Agreement.

Research Resources

  • In Vivo PKD Models and Reagents
    • PKD1, PKD2, PKHD1 Rodent Models (Biosensors, Reporters, and Cre Lines)
    • Hepato-Renal Fibrocystic Rodent Models
    • PKD Models Biobank
    • Zebrafish PKD Ciliopathy Models
    • Custom Animal Models
    • Preclinical Testing
  • Cell Models
    • Mouse Kidney Cell Lines, Primary Cells, Embryonic Fibroblasts, IMCD Cells
    • Human PKD & Control Primary Cells and Biomaterials
    • Mouse Kidney Organoid Culture
    • Ex Vivo Embryonic Kidney Culture
    • Human PKD iPSCs and PKD1/2 Knock Out HEK Cells
    • In Vitro Assays
  • Antibodies and Vectors
    • Polycystin 1 and 2 Antibodies
    • Fibrocystin Antibodies
    • PKD1, PKD2, and PKHD1 Expression Vectors
    • PKD1 cDNA Cloning Kits
    • PKD1 Antibody Validation Kit
    • CRISPR/Cas9 Vectors
  • Clinical Resources and BioMaterials
    • ADPKD Adult and Childhood Clinical Database, Data Dictionary, and Biospecimens
    • Human PKD and Control Primary Cells, Cyst fluid, and Tissue Sections
    • Human Hepato-Renal Fibrocystic Diseases (Clinical Data and BioSpecimens)

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PKD RRC funding is provided by the National Institute of Diabetes and Digestive and Kidney Diseases

 

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