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Zebrafish PKD Ciliopathy Models

Cilia Transition Zone/Ciliopathy Alleles

Bbs5 Null

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Cep164 Null

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Cep290 Null

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JBTS13 Null

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Mks1 Null

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Mks2 Null

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Mks3 Null

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Mks5 Null

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Mks6 Null

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Mksr2 Null

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Nek8 Null

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Nphp1 Allele 2

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Nphp1 Null

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NPHP14 Null

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Nphp4 Allele 2

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Nphp4 Null

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Motile Cilia Alleles

Gas8 Null

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IFT Alleles

Ift172 Null

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Material Transfer Agreement.

Research Resources

  • In Vivo PKD Models and Reagents
    • PKD1, PKD2, PKHD1 Rodent Models (Biosensors, Reporters, and Cre Lines)
    • Hepato-Renal Fibrocystic Rodent Models
    • PKD Models Biobank
    • Zebrafish PKD Ciliopathy Models
    • Custom Animal Model and Pre-clinical Testing Services
  • Cell Models
    • Mouse Kidney Cell Lines, Primary Cells, Embryonic Fibroblasts, IMCD Cells
    • Human PKD & Control Primary Cells and Biomaterials
    • Mouse Kidney Organoid Culture
    • Ex Vivo Embryonic Kidney Culture
  • Antibodies and Vectors
    • Polycystin 1 and 2 Antibodies
    • Fibrocystin Antibodies
    • PKD1 Antibody Validation Kit
    • PKD1 cDNA Cloning Kit
    • CRISPR/Cas9 Vectors
    • PKD1, PKD2, and PKHD1 Expression Vectors
  • Clinical Resources and BioMaterials
    • ADPKD Cohorts (Clinical Data)
    • ADPKD Cohorts (BioSpecimens)
    • Human ADPKD Kidneys (Primary Cells and Biomaterials)
    • Human Hepato-Renal Fibrocystic Diseases (Clinical Data and BioSpecimens)

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PKD RRC funding is provided by the National Institute of Diabetes and Digestive and Kidney Diseases

 

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