Description: This conditional floxed mouse model harbors LoxP sites flanking exons 4 through 6 of the Ift88 gene. Homozygous mice are phenotypically normal. When bred with a Cre recombinase mouse line, offspring lack expression of Ift88 in the Cre targeted tissue. This mouse model may be useful to study human genetic ciliopathies.
Note: Additional combinations of alleles are available upon request