PKD2 Flox; Pax8-rtTA; tetO-7-Cre; mTmG

Description: This strain caries the PKD2 Floxed allele crossed with Pax8-rtTA; tetO-7-Cre and the mTmG Cre reporter. Treatment with tetracycline/doxycycline induces deletion of PKD2 in the proximal and distal tubules and the collecting duct system of both embryonic and adult kidney. Cre-recombinase activity is reflected by a switch from expression of mTomato prior to mGFP.

Contact
: info@pkd-rrc.org

Note
: Additional combination of alleles can be performed upon request

Pkd2-flfl

pax8rtta-strain

tetocre-strain

mTmG

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