PKD1 Flox; Pax8-rtTA; tetO-7-Cre; mTmG

Description: This strain caries the PKD1 Floxed allele crossed with Pax8-rtTA; tetO-7-Cre and the mTmG Cre reporter. Treatment with tetracycline/doxycycline induces deletion of PKD1 in the proximal and distal tubules and the collecting duct system of both embryonic and adult kidney. Cre-recombinase activity is reflected by a switch from expression of mTomato prior to mGFP.

Contact
: info@pkd-rrc.org

Note
: Additional combination of alleles can be performed upon request

pkd1flox-strain

pax8rtta-strain

tetocre-strain

mTmG

Please note: There may be additional costs for the materials and shipping associated with your requests. You will be contacted directly by the provider regarding these costs.