- In vivo PKD Models and Reagents
- PKD1, PKD2, PKHD1 Rodent Models (Biosensors, Reporters, and Cre Lines)
- Mouse Biosensor and Reporter Lines
- CiliaGFP: Expresses GFP-tagged SSTR3 in all cilia
- GCaMP6F Ca2+ Biosensor: Expresses a cytosolic Ca2+ reporter
- IRG Reporter: Expresses dsRed ubiquitously before Cre expression and GFP after recombination
- mTmG Reporter: Expresses dTomato ubiquitously before Cre expression and GFP after recombination
- R26tdTomato Reporter: Expresses tdTomato after Cre recombination
- Rosa26 LacZ Reporter: Expresses LacZ after Cre recombination
- Mouse Cre and Flp Lines
- Multi-Allele Mouse Lines
- Pkd1 Flox; CAGG-CreERT2; Rosa26: Ubiquitous deletion of Pkd1 after Tamoxifen induction
- Pkd1 Flox; HoxB7-Cre: Deletion of Pkd1 in tubular segments derived from the ureteric bud
- Pkd1 Flox; KspCre: Distal and collecting duct specific deletion of Pkd1
- Pkd1 Flox; Pax8-rtTA; tetO-7-Cre; mTmG: Nephron specific deletion of Pkd1 after Doxycycline induction with a fluorescent reporter
- Pkd1 Flox; Pax8-rtTA; tetO-7-Cre: Nephron specific deletion of Pkd1 after Doxycycline induction
- Pkd1 Flox; PKHD1-Cre: Collecting duct specific deletion of Pkd1
- Pkd1 Flox; Rosa26-CreER: Allows global deletion of Pkd1 via tamoxifen injection
- Pkd1flox; mTmG: Pkd1 conditional allele with a fluorescent reporter
- PKD2 Flox; CAGG-CreERT2: Ubiquitous deletion of Pkd2 after Tamoxifen induction
- Pkd2 Flox; GCaMP6F: Pkd2 conditional allele with a cytosolic Ca+2 reporter
- Pkd2 Flox; Ift88 Flox; CAGG-CreERT2: Simultaneous ubiquitous deletion of Pkd2 and Ift88 after Tamoxifen induction
- Pkd2 Flox; Ift88 Flox; mTmG: Pkd2 and Ift88 conditional alleles with a fluorescent reporter
- Pkd2 Flox; Ksp-Cre: Distal and collecting duct specific deletion of Pkd2
- Pkd2 Flox; mTmG: Pkd2 conditional allele with a fluorescent reporter
- Pkd2 Flox; Pax8-rtTA; tetO-7-Cre: Nephron specific deletion of Pkd2 after Doxycycline induction
- Pkd2 Flox; Pkhd1-Cre: Collecting duct specific deletion of Pkd2
- Pkd2 Flox; Rosa26-CreER: Global deletion of Pkd2 after tamoxifen induction
- PKD1 Single Allele Strains Mouse Models
- PKD2 Single Allele Strains Mouse Models
- PKHD1 Single Allele Strains Mouse Models
- PKHD1Â Rat Models
- Mouse Biosensor and Reporter Lines
- PKD1, PKD2, PKHD1 Rodent Models (Biosensors, Reporters, and Cre Lines)
