2025 Symposium Recordings
Please click on the day and session title to view the recording.
Welcome-Day 1 Session 1: GLIS2—A Player in Polycystin Signaling and PKD Therapy
Welcome and Day 1 Introduction
Terry Watnick, M.D., Professor of Medicine, Joan B. and John H. Sadler Professor in Nephrology,
and Principal Investigator, PKD RRC Coordinating Site, University of Maryland School of Medicine
The Patient Experience: Our Stories and Your Impact
PEG-Susan Gleason
Roles of GLIS2 and GLIS3 in Normal Kidney and Cystic Kidney Disease
Anton M. Jetten, Ph.D., Deputy Chief of the Immunity, Inflammation, and Disease Laboratory, National Institute of Environmental Health Sciences, NIH
Abstract Presentation:
Single-nucleus Multi-omics Profiling of Mouse Polycystic Kidney Disease Identifies GPRC5A as a Conserved Cyst Lining Cell Marker
Yoshiharu Muto, M.D., Ph.D., The University of Texas Southwestern Medical Center
Day 1 Session 2: From Data to Discovery—Exploring Multidisciplinary Approaches in Genomics
Mapping Diversity and Development in the Mammalian Kidney Through Spatial Transcriptomics
Andrew P. McMahon, Ph.D., FRS, Research Professor of Biology and Biological Engineering, Merkin Institute for Translational Research, California Institute of Technology
Discovering Mechanisms of Human Kidney Disease From Polygenic Kidney Disease Loci
Gabriel B. Loeb, M.D., Ph.D., Assistant Professor, University of California, San Francisco (UCSF)
Day 1 Session 3: Consortium Overview—A Five-Year Review
Subcommittee 1 – Cell, Owen M. Woodward, Ph.D., Associate Professor of Physiology and Medicine, University of Maryland Baltimore
Subcommittee 2 – Clinical, Stephen Seliger, M.D., M.S., Associate Professor of Medicine, University of Maryland Baltimore
Subcommittee 3 – In Vivo, Courtney “CJ” Haycraft, Ph.D., Associate Director, Transgenic and Genetically Engineered Models Core, University of Alabama at Birmingham
Subcommittee 4 – Molecular, Feng Qian, Ph.D., Professor of Medicine, University of Maryland Baltimore
Subcommittee 5 – Preclinical Assessment, Michal Mrug, M.D., Ph.D., Professor of Medicine, University of Alabama at Birmingham
Day 1 Session 4: Clinical Session
Targeting Adiposity and Caloric Restriction in ADPKD
Kristen Nowak, Ph.D., Associate Professor, Division of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus
Evidence for Health Disparities in the Management of Autosomal Dominant Polycystic Kidney Disease in the United States
Arlene Chapman, M.D., Professor of Medicine and Chief, Section of Nephrology, The University of Chicago
ARPKD – Current Clinical Perspectives
Kathrin Burgmaier, M.D., Professor, Division of Pediatric Nephrology, Immunology, and Hypertension, University of Cologne
Abstract Presentation:
Heterozygous Variants in IFT122, WDR19 and WDR35 Cause ADPKD Spectrum Phenotypes
Dan A. Col0mbo, Beth Israel Deaconess Medical Center
Welcome – Day 2 Session 1: Therapeutic Targets in PKD
Welcome and Day 2 Introduction
Brad Yoder, Ph.D., UAHSF Endowed Chair in Biomedical Research, Professor and Chair of the Department of Cell, Developmental and Integrative Biology, The University of Alabama at Birmingham
Reconstructing Tissue Microenvironment to Better Emulate Polycystic Kidney Disease
Yun Xia, Ph.D., Assistant Professor, Provost’s Chair in Stem Cell Biology, Nanyang Technological University
Addressing the Therapeutic Potential of Bempedoic Acid in PKD: From Pre-Clinical Work to the BEAT-PKD Clinical Trial
Nuria Pastor-Soler, M.D., Ph.D., Associate Professor of Medicine, Associate Vice Chair for Faculty Development, USC
Discovery of the Effect of Caloric Restriction in ADPKD Leading to the PAPP-A Story
Eduardo Chini, M.D., Ph.D., Anesthesiologist, Mayo Clinic
Abstract Presentation:
Alleviating Kidney Cyst Growth Through Genetic and Therapeutic Targeting of Methylation-controlled J Protein
Marie-Louise T Monaghan, Ph.D., University of Colorado Anschutz Medical Campus
Day 2 Session 2: Advances in Other Renal Cystic Diseases
The Role of the Co-Chaperone DNAJB11 In ADPKD: Molecular Mechanisms and Cellular Origin of Cyst Formation
Michael Köttgen, Ph.D., Professor of Nephrology, University Medical Center – University of Freiburg
The Role of IFT Proteins in Monoallelic Polycystic Kidney Disease
Peter Harris, Ph.D., Professor of Cellular Biology, Mayo Clinic
Abstract Presentation:
Kidney Organoids Demonstrate that the Stimulatory G-protein Coupled Receptor PTH1R Drives a cAMP-pPKA-pCREB Axis in Developmental Polycystic Kidney Disease
Humayra Afrin, M.D., Ph.D., Mayo Clinic
Day 2 Session 3: Beyond the Kidney
Targeting a TGFβ-matrix-Integrin Axis Halts the Progression of Polycystic Liver Disease
Scott Waddell, Ph.D., CSO Postdoctoral Research Fellow, The University of Edinburgh
Sensing a Stretch: Cardiac Polycystins, Natriuretic Peptides and Hypertension
Ivana Y. Kuo, Ph.D., Assistant Professor, Department of Cell and Molecular Physiology, Loyola University Chicago
Polycystins Recruit Cargo to Distinct Ciliary Extracellular Vesicle Subtypes
Maureen Barr, Ph.D., Professor of Genetics, Rutgers University
Abstract Presentation:
The Nutrient Sensing mTOR Pathway in Renal Cystogenesis
Flaviane de Fatima Silva, Ph.D., University of Massachusetts Chan Medical School
Day 2 Trainee Workshop: Meet with Successful Young Investigators
Crafting a Successful Research Statement
Whitney Besse, M.D., Assistant Professor, Department of Internal Medicine, Section of Nephrology, Yale School of Medicine
From Ph.D. to Start-Up: The Importance of Founder-Led Biotech in Career Planning
Demetri Maxim, M.S., Chief Executive Officer, Nephrogen
Transitioning from Ph.D. and Postdoc to a Research Career in Industry: Timing Is Everything—Choosing Between Academia and Industry Careers
Shamim Ahmad, Ph.D., Executive Director, Precigen
Building a Career in Medical Affairs
Cibele Pinto, Ph.D., Senior Director, Medical Strategy, Global Medical Affairs, Otsuka Pharmaceutical
