Pkhd1 3xHA: Endogenously HA-tagged Pkhd1 model ARPKD

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Description: This knock-in mouse model has a triple HA tag at the C-terminal tail of PKHD1 and produces a fully functional fibrocystin protein. Homozygous mice are phenotypically normal.
Contact: info@pkd-rrc.org

Pkhd1 Delta 3-4: Pkhd1 mutant model ARPKD

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Description: This mouse model has a deletion of PKHD1 exons 3 through 4. Heterozygous mice are phenotypically normal. Homozygous mice develop congenital hepatic fibrosis.

Contact: info@pkd-rrc.org

Pkhd1 Delta 67: Pkhd1 mutant model ARPKD

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Description: This mouse model lacks PKHD1 exon 67. Homozygous mice are phenotypically normal.
Contact: info@pkd-rrc.org