Description: A Halo Tag was inserted in place of the STOP codon at the C terminus of Pkd2 within exon 15. The resulting allele produces a PC2:Halo fusion protein from the endogenous locus. The homozygous mice are viable and fertile. These mice can be used for in vivo labeling of PC2.
Contact: info@pkd-rrc.org
Description: This knock-out mouse model has a deletion of PKD2 exons 11 through 13. Heterozygous mice are phenotypically normal. Homozygous mice are embryonically lethal at mid-gestation.
Contact: info@pkd-rrc.org
Description: This conditional PKD2 floxed mouse model harbors LoxP sites flanking exons 11 through 13. Homozygous mice are phenotypically normal. When bred with a Cre recombinase mouse line, offspring lack expression of PKD2 in the Cre targeted tissue.
Contact: info@pkd-rrc.org
