Pkd2 Heterozygous: Pkd2 knock-out allele

Description: This knock-out mouse model has a deletion of PKD2 exons 11 through 13. Heterozygous mice are phenotypically normal. Homozygous mice are embryonically lethal at mid-gestation.
Contact: info@pkd-rrc.org

Pkd2 Flox: Pkd2 conditional allele

Description: This conditional PKD2 floxed mouse model harbors LoxP sites flanking exons 11 through 13. Homozygous mice are phenotypically normal. When bred with a Cre recombinase mouse line, offspring lack expression of PKD2 in the Cre targeted tissue.
Contact: info@pkd-rrc.org