Kansas PKD RTCC

Kansas PKD RTCC
Clinical Research Core

Contact: Clinical Research Core, Alan Yu, MD, Core Director; info@pkd-rrc.org                                                                                                                            Biospecimen Core, Darren Wallace, PhD, Core Director; info@pkd-rrc.org

Core Resources: Human Biospecimens

Early PKD Observational Cohort Study (EPOC): Biosamples collected from ADPKD patients during the earliest stages of the disease, that are linked to a longitudinal follow-up database with serial kidney imaging studies, and clinical outcomes.

Biorepository:

  • Urine
  • Urinary exosomes
  • Plasma
  • Sera
  • DNA

Maryland PKD RTCC

Maryland PKD RTCC
Clinical and Translational Core

ClinicalTrials.Gov Identifier NCT01873235

Contact: Stephen Seliger, Core Director; info@pkd-rrc.org

Core Resources: Human Biospecimens

Study #1: Longitudinal Cohort Study of adult ADPKD patients without ESRD and eGFR>15 ml/min/1.73m2
N=198 participants with baseline samples; ongoing repeated sample collection after 3 years

Biorepository:

  • Urine – 10 ml aliquots
  • Plasma – 0.5 ml aliquots
  • Sera – 0.5 ml aliquots
  • DNA – isolated from peripheral blood mononuclear cells (baseline visit)