Description: This conditional Bbs5 floxed mouse model harbors LoxP sites flanking exons 3 through 4. Homozygous mice are phenotypically normal. When bred with a Cre recombinase mouse line, offspring lack expression of Bbs5 in the Cre targeted tissue.
Contact: info@pkd-rrc.org
Note: Additional combinations of alleles are available upon request
Description: This mouse model carries a lacZ cassette and a Neomycin gene inserted in intron 2 of the Bbs5 gene that disrupts expression of the Bbs5 protein. Heterozygous mice are phenotypically normal. Homozygous mice develop retinal defects and obesity.
Contact:info@pkd-rrc.org
Note: Additional combinations of alleles are available upon request
Description: This mouse model carries a lacZ cassette and a Neomycin gene inserted in intron 5 of the Mks6 (Cc2d2a) gene that disrupts expression of the Mks6 protein.
Contact:info@pkd-rrc.org
Note: Additional combinations of alleles are available upon request
