Description: This transgenic mouse model expresses Cre recombinase under the control of a tetracycline-responsive promoter element (TRE or tetO) and is an effective tool for inducible, tissue-specific studies. When bred with another transgenic mouse expressing the reverse tetracycline-controlled transactivator protein (rtTA) or tetracycline-controlled transactivator protein (tTA) the Cre mediated recombination is induced by doxycycline.
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